Genome Editing With CRISPR-Cas9

Genome Editing With CRISPR-Cas9


This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at .

Images and footage courtesy of Sputnik Animation, the Broad Institute of MIT and Harvard, Justin Knight and pond5.


31 thoughts on “Genome Editing With CRISPR-Cas9”

  1. I got mine on eBay and now have blue eyes, blond hair and can live forever, I can even self-indulge to create a zero point energy field thereby turn myself into a Merkaba in order to travel the universe, including time travel, travel to other dimensions, and have superhuman powers. Amazing! The only downside was those stupid instructions, because they weren’t worth a fuck because they were written in Cuniform so I had to call up some of my Pleiadians friends from the Pleiades.

  2. If you want to permanently change some genome in a human, dont you need crispr to enter every cell to change it? How does this work on the bigger scale? What good is it to just edit the genome of a single cell ?

  3. #StopgivingillegalimigrantfagsfreemoneyandahomeandfundtheNHS. *cough* Britain.

  4. Couldn’t you code a virus with Cas 9 to were the virus infects a certain type of cell and then it destroys the cell and replaces it with an engineered copy

  5. It should only be used for people suffering from genetic disorders and not for showoff.

  6. Incredibly useful. Finally, I understand the fundamental principle of CRISPR-Cas9. Thank you

  7. The problem is when they cut out the bad gene, what are they really going to replace it with? That’s the problem right there!

  8. Sempre achei fantástica essa descoberta, e comento com meus colegas do IFRJ – Campus Duque de Caxias.

  9. How does this technique affect the phenotype of the organism on a somatic level (how would performing CRISPR on, say, a mouse, replacing a gene for eye color, change the eye color on the mouse as a whole, as opposed to a single iris muscle cell)?

  10. Every cell in our body [assuming that we are talking of diploid cells, that is, with 46 nuclear chromosomes] has 6 billion, not 3 billion “letters”

  11. *G A T T A C A®* + *X-MEN®* *circa © 2025*

    Exclusive patents granted to Broad Institute of MIT and Harvard; UC Berkeley; GSK; Pfizer; Merck, Novartis, Monsanto, _inter alia_ since *© 2005.* 🤔

  12. I know it is not easy as it sounds but can you actually target the cancer causing gene, i.e. ATGCAA is the gene causing cancer. By inserting the guide RNA correctly and complementary (UACGUU) then allowing matches to occur in the nucleus with the help of Cas9. The cancer causing gene could be disabled by a cut of the DNA (knockout of that specific gene in every cancer cell that the guide RNA is inserted to)?

  13. How is this not as much popularised as Moon Landing ??!!

    Wow… Thank you to all the people in achieving this… I am not sure, I will be the benefactor of this, given the time it needs to enter the Medical field .. I hope and I am sure, it will sure change the way we treat Patients.

  14. The first statement of this video is dead wrong! not every cell in our bodies contains a copy of our DNA. Most of the cells in a human body are Bacteria and so don’t have eukaryotic genomes thus not human DNA (note. some bacteria may have segments of human DNA in some bacteria). Not to mention Mature Red Blood cells don’t have DNA either. This may seem nit picky but it is an important detail.

  15. Just let me die unhealthy happily in return of the lord. Man has always been the driving force to his own demise. The ppl that created these things dont love humans really think about it this world is an evil one thats a tool of the evil ones . to concrete that you are not good the way you are.. Feel a little lonely and depressed anyone? All this tech is worthy of the trash can. We can build it better than ever before. Do you know why we hack to make things that are not broken broken then try to fix them differently the problem lies in that understand. For this tech. Awareness of self and surroundings teaching and sharing knowledge can fix all the generations after us. We have learned a lot about plants and animals recently in yhe past 18yrs have you shared alot.

  16. CRISPR is the triumph of rape. No consideration is being given to consent issues. Genes make people and people have preferences. People refuse intimacy with some other people. No consideration is being given to the preferences of embodied genes. Rapist genes are assuming full control of nonrapist genes. This MUST be stopped!

    This will be one of the reasons for the return of Jesus. To stop the rape!

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